Publicaciones

Publicaciones

AñoTítuloAutores CIFARTipoRevistaLink
2023The Antiproliferative Activity of a Mixture of Peptide and Oligosaccharide Extracts Obtained from Defatted Rapeseed Meal on Breast Cancer Cells and Human FibroblastsCaroline WeinsteinArtículoFoods 12(2):253link
2023Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proof-of-concept phase II trialCarolina CamposArtículoPLoS ONE 18(1): e0280335link
2023Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectivesLuis Espinoza y Jaime MellaArtículoSteroids 190, 109153link
2023In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studiesJaime MellaArtículoJournal of Biomolecular Structure and Dynamicslink
2023Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamicsJaime MellaArtículoJournal of the Serbian Chemical Society 88(1):25-39link
2023Método para preparar nanoemulsiones antifitopatógenas a base de partes aéreas de P. glandulosa y de E. IllinitaIván MontenegroPatenteInstituto Nacional de Propiedad Intelectual
2023Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) DrimenolJaime Mella, Iván Montenegro, Luis Espinoza, Waleska Vera y Mauricio CuellarArticulosMolecules 28(9):3959link
2022QSAR-driven synthesis of antiproliferative chalcones against SH-SY5Y cancer cells: Design, biological evaluation, and redesignCaroline Weinstein, Jaime Mella y Mauricio CuellarArtículoArch Pharm 355(7):2200042link
2022Involvement of Inflammation and Its Resolution in Disease and TherapeuticsCaroline Weinstein y Carolina CamposArtículoInternational Journal of Molecular Sciences 23(18):10719.link
2022Formulation of water soluble Buddleja globosa Hope extracts and characterization of their antimicrobial properties against Pseudomonas aeruginosaDaniel Moraga y Tania BahamóndezArtículoFrontiers in Pharmacology 13: 921511link
2022Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking AnalysisMauricio CuellarArtículoMolecules 27(14):4387link
2022New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione ReductaseMauricio CuellarArtículoPharmaceutics 14(6):1121link
2022In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.Jaime MellaArtículoPharmaceutics 14(6):1294link
2021Antiproliferative Rapeseed Defatted Meal Protein and Their Hydrolysates on MCF-7 Breast Cancer Cells and Human Fibroblasts.Caroline WeinsteinArtículoFoods 10(2):309link
2021Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor SignalingCaroline WeinsteinArtículoInternational Journal of Molecular Sciences. 22(3):1069link
2021Natural isoflavonoids in invasive cancer therapy: From bench to bedsideCaroline WeinsteinArtículoPhytotherapy Research 35(8):4092-4110link
2021Avances y desafíos en las vacunas el para control de la pandemia por COVID-19Caroline WeinsteinEditorialARS Médica Revista de Ciencias Médicas 46(2)link
2021Alfabetización estadística y comunicación de riesgo para la vacunación contra la COVID-19:una revisión de alcanceCaroline WeinsteinArtículoPan American Journal of Public Health 45link
2021El caso de aducanumab ¿Más esperanza que ciencia?Caroline WeinsteinArtículoARS Médica Revista de Ciencias Médicas 46(3)link
2021Inhibition of Caco-2 and MCF-7 cancer cells using chalcones: synthesis, biological evaluation and computational studyCaroline WeinsteinArtículoNatural Product Research 36(17): 4404-4410link
2021The science behind the development of anti-SARS-CoV-2 vaccinesCaroline WeinsteinArtículoRevista de Farmacologia de Chile 14(1):6-14link
2021Mieloma múltiple. Experiencia de 9 años en el Hospital Naval Almirante NefMagdalena CortésArtículoARS Médica Revista de Ciencias Médicas 46(2), 16–24.link
2021Differences in volatile emissions between healthy and gall-induced branches of Haplopappus foliosus (Asteraceae)Waleska VeraArtículoBiochemical Systematics and Ecology 98: 104309link
2021Innovating on inhaled bioequivalence: A critical analysis of the current limitations, potential solutions and stakeholders of the processTania Bahamóndez y Daniel MoragaArtículoPharmaceutics 13(7):1051link
2021Nuevas perspectivas para el tratamiento de la infección por Helicobacter pyloriTania BahamóndezArtículoARS Médica Revista de Ciencias Médicas 46(2), 60-69link
2021Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT6 Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity.Jaime MellaArtículoPharmaceuticals 14(6):528.link
2021Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitorsJaime Mella y Mauricio CuellarArtículoBioorganic Chemistry 108: 104689link
2020In vivo efficacy of a dry powder formulation of ciprofloxacin-copper complex in a chronic lung infection model of bioluminescent Pseudomonas aeruginosaTania Bahamóndez y Daniel MoragaArtículoEuropean Journal of Pharmaceutics and Biopharmaceutics 152:210-217link
2020In vitro Notch-mediated adjuvant immunogenic potency is induced by combining QS-21 and MPL in a co-culture model of PBMC and HUVEC cellsCarolina CamposArtículoToxicology in Vitro 68:104947link
2020Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed LigandsJaime MellaArtículoMolecules 25(20):4614link
2020Notch receptor expression in Trypanosoma cruzi-infected human umbilical vein endothelial cells treated with benznidazole or simvastatin revealed by microarray analysis.Jaime MellaArtículoCell Biology International 44(5):1112-1123link
2020Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease
Jaime MellaArtículoEuropean Journal of Medicinal Chemistry 198:112368link
2020DARK Classics in Chemical Neuroscience: Heroin and DesomorphineJaime MellaArtículoACS Chemical Neuroscience 11(23):3905–3927link
2020Autorización de uso de emergencia primera vacuna RNA para COVID-19 en ChileCaroline WeinsteinEditorialRevista Médica de Chile 148(12)link
2019Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid LigandsJaime MellaArtículoInternational Journal of Molecular Sciences. 20(10):2510.link
2019Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogsJaime MellaArtículoToxicology in Vitro 54:375-390link
2019Design, synthesis, antifungal activity, and structure–activity relationship studies of chalcones and hybrid dihydrochromane–chalconesLuis Espinoza, Alejandro Madrid, Jaime Mella y Mauricio CuellarArtículoMolecular Diversity 24:603–615link
2019Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity.Mauricio CuellarArtículoChemistry Select 4(26):7698-7703link
2019Lack of association between the IL6R GENE ASP358ALA Variant (RS2228145), IL-6 plasma levels and treatment resistance in chilean schizophrenic patients treated with clozapineCarolina CamposArtículoSchizophrenia Research and Treatment 5601249link
2019Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cellsCecilia Rubio, Natalia Quiñones y Caroline WeinsteinArtículoBiological Research 52:55link
2019Impacto del Polimorfismo Genético de CYP2D6 en la Enfermedad de Parkinson
Caroline WeinsteinArtículoRevista de Farmacologia de Chile 12(1):21-33link
2019Experimental and theoretical approaches in the study of phenanthroline‐tetrahydroquinolines for Alzheimer's diseaseRocío ÁlvarezArtículoChemistry Open 8(5):627-636link
2019Novel Coumarin‐Quinoline Hybrids: Design of Multitarget compounds for Alzheimer's Disease
Rocío ÁlvarezArtículoChemistry Select 4(2):551-558link
2019Antigrowth activity and induction of apoptosis in human melanoma cells by Drymis winteri forst extract and its active components.Iván Montenegro, Mauricio Cuellar y Alejandro MadridArtículoChemico-Biological Interactions 305:79-85link
2019La Farmacopea Chilena versión 2016 y su aporte a la medicina tradicionalPatricia Carreño, Marcela Escobar, Cecilia Rubio y Caroline WeinsteinArtículoCuadernos Médico Sociales 60(3)link
2019Overview of the delivery technologies for inhalation aerosols. Inhalation Aerosols: Physical and Biological Basis for TherapyDaniel MoragaCapítulo de libroInhalation aerosolslink
2019A critical perspective on future developments based on the knowledge we have nowTania BahamóndezCapítulo de libroInhalation aerosolslink
2018Mass Median Plume Angle: A novel approach to characterize plume geometry in solution based pMDIsDaniel MoragaArtículoInternational Journal of Pharmaceutics 543; (1–2):376-385link
2018Effect of Inhalation Flow Rate on Mass-Based Plume Geometry of Commercially Available Suspension pMDIsDaniel MoragaArtículoThe AAPS journal 20:84link
2018A modified USP induction port to characterize nasal spray plume geometry and predict turbinate deposition under flowDaniel MoragaArtículoInternational Journal of Pharmaceutics 548(1):305-313link
2018Development, characterization, and in vitro testing of co-delivered antimicrobial dry powder formulation for the treatment of Pseudomonas aeruginosa biofilmsDaniel Moraga y Tania BahamóndezArtículoJournal of Pharmaceutical Sciences 107(8):2172-2178link
2018Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite ControlCarolina CamposArtículoFrontiers in Microbiology 9:1961link
2018t-Resveratrol Protects against Acute High Glucose Damage in Endothelial CellsRocío ÁlvarezArtículoPlant Foods for Human Nutrition 73, pages235–240link
2018Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic ProfilesJaime MellaArtículoMolecules 23(5):1191link
2018Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line quantitative structure


Alejandro Madrid, Caroline Weinstein, Jaime Mella y Mauricio CuellarArtículoMedicinal Chemistry Research 27, 2414–2425link
2018Antifeedant effect of polygodial and drimenol derivatives against Spodoptera frugiperda and derivatives against Spodoptera frugiperda and Epilachna paenulata and quantitative structure-activity analysisIván Montenegro, Alejandro Madrid y Mauricio CuellarArtículoPest Management Science 74(7):1623-1629link
2018(-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of angucyclinonesNatalia Quiñones, Luis Espinoza y Mauricio CuellarArtículoMolecules 23(6):1422link
2018Percepcion social de la utilidad, riesgos y beneficios de la ciencia y la tecnologia en ChileMarcelo ArancibiaLibro
2017Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies.Luis Espinoza y Jaime MellaArtículoInternational Journal of Molecular Sciences. 18(12):2734.link
2017Aplicaciones clínicas de células madres derivadas de tejido adiposo y aspectos relacionados con buenas prácticas de manufactura.
Patricia Carreño y Caroline WeinsteinArtículoAnales de la Real Academia Nacional de Farmacia. 83:329-402link

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