2023 | The Antiproliferative Activity of a Mixture of Peptide and Oligosaccharide Extracts Obtained from Defatted Rapeseed Meal on Breast Cancer Cells and Human Fibroblasts | Caroline Weinstein | Artículo | Foods 12(2):253 | link |
2023 | Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proof-of-concept phase II trial | Carolina Campos | Artículo | PLoS ONE 18(1): e0280335 | link |
2023 | Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives | Luis Espinoza y Jaime Mella | Artículo | Steroids 190, 109153 | link |
2023 | In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies | Jaime Mella | Artículo | Journal of Biomolecular Structure and Dynamics | link |
2023 | Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics | Jaime Mella | Artículo | Journal of the Serbian Chemical Society 88(1):25-39 | link |
2023 | Método para preparar nanoemulsiones antifitopatógenas a base de partes aéreas de P. glandulosa y de E. Illinita | Iván Montenegro | Patente | Instituto Nacional de Propiedad Intelectual | |
2023 | Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol | Jaime Mella, Iván Montenegro, Luis Espinoza, Waleska Vera y Mauricio Cuellar | Articulos | Molecules 28(9):3959 | link |
2022 | QSAR-driven synthesis of antiproliferative chalcones against SH-SY5Y cancer cells: Design, biological evaluation, and redesign | Caroline Weinstein, Jaime Mella y Mauricio Cuellar | Artículo | Arch Pharm 355(7):2200042 | link |
2022 | Involvement of Inflammation and Its Resolution in Disease and Therapeutics | Caroline Weinstein y Carolina Campos | Artículo | International Journal of Molecular Sciences 23(18):10719. | link |
2022 | Formulation of water soluble Buddleja globosa Hope extracts and characterization of their antimicrobial properties against Pseudomonas aeruginosa | Daniel Moraga y Tania Bahamóndez | Artículo | Frontiers in Pharmacology 13: 921511 | link |
2022 | Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis | Mauricio Cuellar | Artículo | Molecules 27(14):4387 | link |
2022 | New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase | Mauricio Cuellar | Artículo | Pharmaceutics 14(6):1121 | link |
2022 | In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia. | Jaime Mella | Artículo | Pharmaceutics 14(6):1294 | link |
2021 | Antiproliferative Rapeseed Defatted Meal Protein and Their Hydrolysates on MCF-7 Breast Cancer Cells and Human Fibroblasts. | Caroline Weinstein | Artículo | Foods 10(2):309 | link |
2021 | Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling | Caroline Weinstein | Artículo | International Journal of Molecular Sciences. 22(3):1069 | link |
2021 | Natural isoflavonoids in invasive cancer therapy: From bench to bedside | Caroline Weinstein | Artículo | Phytotherapy Research 35(8):4092-4110 | link |
2021 | Avances y desafíos en las vacunas el para control de la pandemia por COVID-19 | Caroline Weinstein | Editorial | ARS Médica Revista de Ciencias Médicas 46(2) | link |
2021 | Alfabetización estadística y comunicación de riesgo para la vacunación contra la COVID-19:una revisión de alcance | Caroline Weinstein | Artículo | Pan American Journal of Public Health 45 | link |
2021 | El caso de aducanumab ¿Más esperanza que ciencia? | Caroline Weinstein | Artículo | ARS Médica Revista de Ciencias Médicas 46(3) | link |
2021 | Inhibition of Caco-2 and MCF-7 cancer cells using chalcones: synthesis, biological evaluation and computational study | Caroline Weinstein | Artículo | Natural Product Research 36(17): 4404-4410 | link |
2021 | The science behind the development of anti-SARS-CoV-2 vaccines | Caroline Weinstein | Artículo | Revista de Farmacologia de Chile 14(1):6-14 | link |
2021 | Mieloma múltiple. Experiencia de 9 años en el Hospital Naval Almirante Nef | Magdalena Cortés | Artículo | ARS Médica Revista de Ciencias Médicas 46(2), 16–24. | link |
2021 | Differences in volatile emissions between healthy and gall-induced branches of Haplopappus foliosus (Asteraceae) | Waleska Vera | Artículo | Biochemical Systematics and Ecology 98: 104309 | link |
2021 | Innovating on inhaled bioequivalence: A critical analysis of the current limitations, potential solutions and stakeholders of the process | Tania Bahamóndez y Daniel Moraga | Artículo | Pharmaceutics 13(7):1051 | link |
2021 | Nuevas perspectivas para el tratamiento de la infección por Helicobacter pylori | Tania Bahamóndez | Artículo | ARS Médica Revista de Ciencias Médicas 46(2), 60-69 | link |
2021 | Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT6 Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity. | Jaime Mella | Artículo | Pharmaceuticals 14(6):528. | link |
2021 | Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors | Jaime Mella y Mauricio Cuellar | Artículo | Bioorganic Chemistry 108: 104689 | link |
2020 | In vivo efficacy of a dry powder formulation of ciprofloxacin-copper complex in a chronic lung infection model of bioluminescent Pseudomonas aeruginosa | Tania Bahamóndez y Daniel Moraga | Artículo | European Journal of Pharmaceutics and Biopharmaceutics 152:210-217 | link |
2020 | In vitro Notch-mediated adjuvant immunogenic potency is induced by combining QS-21 and MPL in a co-culture model of PBMC and HUVEC cells | Carolina Campos | Artículo | Toxicology in Vitro 68:104947 | link |
2020 | Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands | Jaime Mella | Artículo | Molecules 25(20):4614 | link |
2020 | Notch receptor expression in Trypanosoma cruzi-infected human umbilical vein endothelial cells treated with benznidazole or simvastatin revealed by microarray analysis. | Jaime Mella | Artículo | Cell Biology International 44(5):1112-1123 | link |
2020 | Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease
| Jaime Mella | Artículo | European Journal of Medicinal Chemistry 198:112368 | link |
2020 | DARK Classics in Chemical Neuroscience: Heroin and Desomorphine | Jaime Mella | Artículo | ACS Chemical Neuroscience 11(23):3905–3927 | link
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2020 | Autorización de uso de emergencia primera vacuna RNA para COVID-19 en Chile | Caroline Weinstein | Editorial | Revista Médica de Chile 148(12) | link |
2019 | Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands | Jaime Mella | Artículo | International Journal of Molecular Sciences. 20(10):2510. | link |
2019 | Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs | Jaime Mella | Artículo | Toxicology in Vitro 54:375-390 | link |
2019 | Design, synthesis, antifungal activity, and structure–activity relationship studies of chalcones and hybrid dihydrochromane–chalcones | Luis Espinoza, Alejandro Madrid, Jaime Mella y Mauricio Cuellar | Artículo | Molecular Diversity 24:603–615 | link |
2019 | Design, Synthesis and Docking Calculations of Prenylated Chalcones as Selective Monoamine Oxidase B Inhibitors with Antioxidant Activity. | Mauricio Cuellar | Artículo | Chemistry Select 4(26):7698-7703 | link |
2019 | Lack of association between the IL6R GENE ASP358ALA Variant (RS2228145), IL-6 plasma levels and treatment resistance in chilean schizophrenic patients treated with clozapine | Carolina Campos | Artículo | Schizophrenia Research and Treatment 5601249 | link |
2019 | Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells | Cecilia Rubio, Natalia Quiñones y Caroline Weinstein | Artículo | Biological Research 52:55 | link |
2019 | Impacto del Polimorfismo Genético de CYP2D6 en la Enfermedad de Parkinson
| Caroline Weinstein | Artículo | Revista de Farmacologia de Chile 12(1):21-33 | link |
2019 | Experimental and theoretical approaches in the study of phenanthroline‐tetrahydroquinolines for Alzheimer's disease | Rocío Álvarez | Artículo | Chemistry Open 8(5):627-636 | link |
2019 | Novel Coumarin‐Quinoline Hybrids: Design of Multitarget compounds for Alzheimer's Disease
| Rocío Álvarez | Artículo | Chemistry Select 4(2):551-558 | link |
2019 | Antigrowth activity and induction of apoptosis in human melanoma cells by Drymis winteri forst extract and its active components. | Iván Montenegro, Mauricio Cuellar y Alejandro Madrid | Artículo | Chemico-Biological Interactions 305:79-85 | link |
2019 | La Farmacopea Chilena versión 2016 y su aporte a la medicina tradicional | Patricia Carreño, Marcela Escobar, Cecilia Rubio y Caroline Weinstein | Artículo | Cuadernos Médico Sociales 60(3) | link |
2019 | Overview of the delivery technologies for inhalation aerosols. Inhalation Aerosols: Physical and Biological Basis for Therapy | Daniel Moraga | Capítulo de libro | Inhalation aerosols | link |
2019 | A critical perspective on future developments based on the knowledge we have now | Tania Bahamóndez | Capítulo de libro | Inhalation aerosols | link |
2018 | Mass Median Plume Angle: A novel approach to characterize plume geometry in solution based pMDIs | Daniel Moraga | Artículo | International Journal of Pharmaceutics 543; (1–2):376-385 | link |
2018 | Effect of Inhalation Flow Rate on Mass-Based Plume Geometry of Commercially Available Suspension pMDIs | Daniel Moraga | Artículo | The AAPS journal 20:84 | link |
2018 | A modified USP induction port to characterize nasal spray plume geometry and predict turbinate deposition under flow | Daniel Moraga | Artículo | International Journal of Pharmaceutics 548(1):305-313 | link |
2018 | Development, characterization, and in vitro testing of co-delivered antimicrobial dry powder formulation for the treatment of Pseudomonas aeruginosa biofilms | Daniel Moraga y Tania Bahamóndez | Artículo | Journal of Pharmaceutical Sciences 107(8):2172-2178 | link |
2018 | Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control | Carolina Campos | Artículo | Frontiers in Microbiology 9:1961 | link |
2018 | t-Resveratrol Protects against Acute High Glucose Damage in Endothelial Cells | Rocío Álvarez | Artículo | Plant Foods for Human Nutrition 73, pages235–240 | link |
2018 | Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles | Jaime Mella | Artículo | Molecules 23(5):1191 | link |
2018 | Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line quantitative structure
| Alejandro Madrid, Caroline Weinstein, Jaime Mella y Mauricio Cuellar | Artículo | Medicinal Chemistry Research 27, 2414–2425 | link |
2018 | Antifeedant effect of polygodial and drimenol derivatives against Spodoptera frugiperda and derivatives against Spodoptera frugiperda and Epilachna paenulata and quantitative structure-activity analysis | Iván Montenegro, Alejandro Madrid y Mauricio Cuellar | Artículo | Pest Management Science 74(7):1623-1629 | link |
2018 | (-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of angucyclinones | Natalia Quiñones, Luis Espinoza y Mauricio Cuellar | Artículo | Molecules 23(6):1422 | link |
2018 | Percepcion social de la utilidad, riesgos y beneficios de la ciencia y la tecnologia en Chile | Marcelo Arancibia | Libro | | |
2017 | Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies. | Luis Espinoza y Jaime Mella | Artículo | International Journal of Molecular Sciences. 18(12):2734. | link |
2017 | Aplicaciones clínicas de células madres derivadas de tejido adiposo y aspectos relacionados con buenas prácticas de manufactura.
| Patricia Carreño y Caroline Weinstein | Artículo | Anales de la Real Academia Nacional de Farmacia. 83:329-402 | link |